Steffi Oesterreich, Ph.D. - Publications
The articles are listed in chronological order, with the most recent publications at the top. You can download pdf files of many articles by clicking on the [PDF] text by each listing.
2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | Books/Chapters
2006
Jiang S, Meyer R, Kang K, Osborne CK, Wong J, Oesterreich S. Scaffold Attachment Factor SAFB1 suppresses ERa-mediated transcription in part via interaction with N-CoR. Molecular Endocrinology, 20:311-20, 2006. [PDF]
Dobrzycka KM, Kang K, Jiang S, Meyer R, Rao PH, Lee AV, Oesterreich S. Disruption of Scaffold Attachment Factor B1 Leads to TBX2 Up-regulation, Lack of p19ARF Induction, Lack of Senescence, and Cell Immortalization. Cancer Research, 66:7859-63, 2006. [PDF]
Townson SM, Kang K, Lee AV, Oesterreich S. Novel role of the RET finger protein in estrogen receptor-mediated transcription in MCF-7 cells. Biochemical and Biophysical Research Communications, 349:540-8, 2006. [PDF]
2005
Zubairy S, Oesterreich S. Estrogen-repressed genes -- key
mediators of estrogen action?
Breast Cancer Res. 2005;7(4):163-4.
2005 May 24. [PDF]
Ivanova M, Dobrzycka KM, Jiang S, Michaelis K, Meyer R, Kang K, Adkins
B,
Barski OA, Divisova J, Lee AV, Oesterreich S. Scaffold attachment factor
B1
functions in development, growth, and reproduction. Molecular and Cellular
Biology. 25:2995-3006, 2005. [PDF]
2004
Townson SM, Kang K, Lee AV, and Oesterreich S. A Structure-Function Analysis of the ER a Corepressor SAFB1: Identification of a Potent Transcriptional Repression Domain . J Biol Chem. 279:26074-81, 2004. [PDF] .
Lee AV, Chamness G, Oesterreich S. 26th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 3-6 December 2003: update on preclinical and translational research. Breast Cancer Res. 2004 Jan 19;6(2):E10. [PDF]
2003
Lee AV, Schiff R, Cui X, Sachdev D, Yee D, Gilmore AP, Streuli CH, Oesterreich S, Hadsell DL. New Mechanisms of Signal Transduction Inhibitor Action: Receptor Tyrosine Kinase Down-Regulation and Blockade of Signal Transactivation. Clin Cancer Res. 2003 Jan;9(1 Pt 2):516S-23S. [PDF]
Cui X, Zhang P, Deng W, Oesterreich S, Lu Y, Mills G, Lee AV. IGF-I Inhibits Progesterone Receptor Expression in Breast Cancer Cells via the PI3K/Akt/mTOR Pathway: Progesterone Receptor as a Potential Indicator of Growth Factor Activity in Breast Cancer. Mol Endocrinol, 2003 Apr;17(4):575-88. [PDF]
Townson S, Dobrzycka KM, Lee AV, Air M, Deng W, Kang K, Jiang S, Michaelis K, Oesterreich S. SAFB2 – A New SAFB Homolog and Estrogen Receptor Corepressor. J Biol Chem, 2003 May 30;278(22):20059-68. [PDF]
Lee AV, Zhang P, Ivanova M, Bonnette S, Oesterreich S, Rosen JM, Grimm S, Hovey RC, Vonderhaar BK, Kahn CR, Torres D, George J, Mohsin S, Allred DC, Hadsell DL. Developmental and Hormonal Signals Dramatically Alter the Localization and Abundance of Insulin Receptor Substrate Proteins in the Mammary Gland. Endocrinology, 2003 Jun;144(6):2683-94. [PDF]
Oesterreich S , Deng W, Jiang S, Cui X, Ivanova M, Schiff R, Kang K, Hadsell D, Behrens J, Lee AV. Estrogen-mediated downregulation of E-cadherin in breast cancer cells. Cancer Res 63:5203-8, 2003. [PDF]
Dobrzycka KM, Townson SM, Jiang S, Oesterreich S. Estrogen receptor corepressors- A role in human breast cancer? Endocrine-related Cancer, 10: 517-36, 2003. [PDF]
Oesterreich S. Scaffold Attachment Factor SAFB1 and SAFB2: Innocent Bystanders or Critical Players in Breast Tumorigenesis?" Journal of Cellular Biochemistry, 90:653-61, 2003. [PDF]
2002
Townson SM, Ivanova M, Lee AV, Oesterreich S. The role of estrogen in normal breast development and breast cancer. In "Natural and Synthetic Estrogens: Aspects of the Cellular and Molecular Activity. 2002: 33-55. Editors: Dopp E, Stopper H, Alink GM.
2001
Oesterreich S, Zhang P, Guler RL, Sun XH, Curran, EM, Welshons, WV, Osborne, CK, Lee AV. Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin-like growth factor-mediated signaling and growth. Cancer Research 61:5771-5777, 2001. [PDF]
Lee AV, Cui X and Oesterreich S. Cross talk among estrogen receptor, epidermal growth factor, and insulin-like growth factors in human breast cancer. Clinical Cancer Research 7:4429S-4435S, 2001.
2000
Oesterreich S, Zhang Q, Hopp T, Fuqua SAW, Michaelis M, Zhao HH, Davie JR, Osborne CK, Lee AV. Estrogen receptor bone to the antiestrogen tamoxifen strongly interacts with the nuclear matrix protein HET/SAF-B, a novel inhibitor of estrogen receptor-mediated transactivation. Mol Endocrinol 14:369-382, 2000. [PDF]
Lee AV, Gooch LJ, Oesterreich S, Guler RL, Yee D. IGF-1 induced degradation of insulin receptor substrate-1 is mediated by the 26S proteasome and blocked by phosphaditylinositol 3'-kinase inhibition. Mol Cell Biol 20:1489-1496, 2000. [PDF]
Townson S, Zhang Q-P, Clark GM, Osborne CK, Lee AV, Oesterreich S. HET/SAF-B overexpression causes growth arrest and multinuclearity and is associated with aneuploidy in human breast cancer. Clin Canc Res. Vol. 6, 3788-3796. September 2000. [PDF]
Oesterreich S, Allred DC, Mohsin SK, Zhang Q, Wong H, Lee AV, Osborne CK, O’Connell P. High rates of loss of heterozygosity on chromosome 19p13 in human breast cancer. Br J Cancer Feb; 84(4):493-498 2001.
Oesterreich S, Zhang, Q P, Lee A V Inhibition of oestrogen receptor activity by the co-repressor HET/SAF-B is relieved by blockade of histone deacetylase activity Euro J Cancer 36:S39-S46 2000. [PDF]
Oesterreich S, Lee AV, Guler, BL, Sun X, Zhang, QP, Curran, EM, Welshons WV. Oestrogen receptor is a critical component required for insulin-like growth factor (IGF)-mediated signaling and growth in MCF-7 cells. Euro J Cancer 36 S93-S118 2000. [PDF]
1999
Lemieux P, Harvey J, Guise T, Dallas M, Oesterreich S, Yin YY, Selander K, Fuqua S: Low Cell Motility Induced by hsp27 overexpression decreases osteolytic bound metastasis in human breast cancer cells in vivo. J Bone Miner Res 14:1-6, 1999.
Hansen RK, Parra I, Lemieux P, Oesterreich S, Hilsenbeck SG, Fuqua SAW. Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells. Breast Cancer Res Treat 1425:1-10, 1999.
Oesterreich S., Fuqua S.A.W. Tumor Suppressor Genes in Breast Cancer. Endocrine-Related Cancer, 6:405-419, 1999. November 1, 1999 – December 31, 1999. [PDF]
1998
Eskenazi AE, Powers J, Oesterreich S, Fuqua SAW, Pinkas J. Induction of heat shock protein 27 by hydroxyurea and its relationship to experimental metastasis. Clin Exp Metastasis 16:283-290, 1998.
Samuel SK, Spencer VA, Bajno L, Sun J-M, Holth LT, Oesterreich S, Davie JR. In situ cross-linking by cisplatin of nuclear matrix bound transcription factors to nuclear DNA of human breast cancer cells. Cancer Res 58:3004-3008, 1998.
1997
Zhang Q-X, Wolf DM, Borg A, Oesterreich S, Fuqua SAW. Human estrogen receptor tyrosine 537 mutant identified in a metastatic breast tumor confers strong transactivation independent of hormone binding. Cancer Res 57:1244-1249, 1997.
Oesterreich S, Lee AV, Sullivan TM, Samuel SK, Davie JR, Fuqua SAW. Novel nuclear matrix protein HET binds to and influences activity of the hsp27 promoter in human breast cancer cells. J Cell Biochem 67:275-286, 1997. [PDF]
Castles CG, Oesterreich S, Hansen R, Fuqua SAW. Auto-regulation of the estrogen receptor promoter. J Steroid Biochem Molec Biol 62:155-163, 1997.
Hansen RK, Oesterreich S, Lemieux P, Sarge KD, Fuqua SA. Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells. Biochem Biophys Res Commun 239:851-856, 1997.
Dupont BR, Garcia DK, Naylor SL, Oesterreich S. Assignment of SAFB encoding hsp27 ERE-TATA binding protein (HET)/scaffold attachment factor B (SAF-B) to human chromosome 19 band p13. Cytogenet Cell Genet 79:284-285, 1997.
Lemieux P, Oesterreich S, Lawrence JA, Steeg PS, Hilsenbeck SG, Harvey JM, Fuqua SAW. The small heat shock protein hsp27 increases invasiveness but decreases motility of breast cancer cells. Invasion Metastasis 17:113-123, 1997.
1996
Oesterreich S, Hickey E, Weber LA, Fuqua SAW. Basal regulatory promoter elements of the hsp27 gene in human breast cancer cells. Biochem Biophys Res Commun 222:155-163, 1996.
Oesterreich S, Hilsenbeck SG, Allred DC, Ciocca D, Chamness GC, Osborne CK, Fuqua SAW. The small heat shock protein HSP27 is not an independent prognostic marker in axillary lymph node-negative breast cancer patients. Clin Cancer Res 2:1199-1206, 1996.
Books/Chapters:
Oesterreich S, Benndorf R, Reichmann G, Bielka H. Phosphorylation and acylation of the growth- related murine small stress protein p25. NATO ASI Series Vol H 56, 489-493, 1991.
Fuqua, S. A. W. and Oesterreich, S. Lack of Association Between Tumor Necrosis and hsp-27 Expression in Primary Breast Cancer, Editorial Comment. Breast Diseases: A Year Book Quarterly 7(4), 1997.
Lee AV, Oesterreich S, and Fuqua SAW: Estrogen receptor variants in early breast disease and breast cancer progression. In Heppner GH, Visscher DW, Peters WP (eds), Advances in Oncobiology—Breast Cancer, JAI Press, Inc, 1998, pp 117-135.
Townson S, Ivanova M, Lee AV, Oesterreich S. The Role of Estrogen in Normal Breast Development and Breast Cancer. In Natural and Synthetic Estrogens: Aspects of the Cellular and Molecular Activity. In press 2002.